Rank Product analysis

From Organic Design wiki
Revision as of 21:10, 5 March 2007 by Sven (talk | contribs)

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

Rainer Breitling, Patrick Armengaud, Anna Amtmanna, Pawel Herzykb

Overview

Rank Product is a non parametric statistical method of analysing microarray data. It assumes that under the null hypothesis, the order of all items is random, and the probability of findng a specific item among the top r of n items in a list is p = r/n.

Multiplying theses probabilities over i replicates leads to the rank product definition;

[math]\prod_i \over{r_i}{n_i}[/math]

where ri is the rank of the item in the i-th list and ni is the total number of items in the i-th list.

See also