Almost all science follows the principle of Occams Razor and it seems to be truth at the most basic instinctual level too - it's common sense. The organisational principles described here, and the eastern philosophies it is designed in accord with (Taoism and Advaita Vedanta) also work in accord with Occams' razor.
But there seems to be one very fundamental aspect of science that totally violates occams razor, and science itself seems to be in some sort of denial about it. It's the idea that the perceived universe of energy and matter exist independently of perception. It may seem obvious, but never the less, it is an assumption. Of course quantum physics is leading the way in realising the truth, but most quantum physicists themselves think of it as so alien and strange that anyone who thinks it normal must not have understood - this is the perspective of those who do not see that perception and creation are asepcts of the same.
- The Western Model
The dominant scientific model of the universe says that matter and energy exist in chaos and that over time stimulus-response characteristices grew out of systems of equilibrium. Eventually the systems grew in complexity enough that they were able to store and simulate aspects of their environment which allowed their responses to be based on prediction. The stimulus-response loop evolved into perception, and the internal simulation method evolved into memory and imagination.
- The Eastern Model
This cannot be proven false because it's actually real - in the now that our perception is continually creating that is. Although both sides could (and do) argue their fundamentalness for all eternity, Occams Razor favours the East.
We know that we are creating space and time in our minds, because memory and imagination involve the observation of distinct things (in space) undergoing change (over time). It doesn't matter whether we consider those things as some lower form of reality or not, it's the process, the way of it which matters here. The eastern philosophies teach us to observe the goings-on in our own minds carefully and persistently because when an understanding of its workings crystallises, we see that these levels of reality are just relative, and the only truth is the way common to all these levels. The way of space and time, perception and creation.