Difference between revisions of "GGBsnippet.R"

From Organic Design wiki
m (note on 2*slides=p)
m (# {{R}})
 
(5 intermediate revisions by the same user not shown)
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p <- 1000
+
# {{R}}
n <- 10
+
# p (genes) by n (slides) matrix
a.shape  <- parameters[1]
+
# m=p keeping fdr notation
a0.shape <- parameters[2]
+
 
scale    <-   parameters[3]
+
m <- p <- 1000  
 +
nreps <- 5
 +
 
 +
n   <- nreps * 2
 +
pi0 <- 0.95
 +
 
 +
m1 <- round(m * (1-pi0))
 +
m0 <- p - m1
 +
 
 +
params <- c(2.74886, 1.36546, 4.12844) # "IPTG-a parameters"
 +
 
 +
a.shape  <- params[1]
 +
a0.shape <- params[2]  
 +
scale    <- params[3]  
 
      
 
      
 
DEscales <- rgamma(2*m1, shape=a0.shape, rate=scale)
 
DEscales <- rgamma(2*m1, shape=a0.shape, rate=scale)
 
EEscales <- rgamma(m0 , shape=a0.shape, rate=scale)
 
EEscales <- rgamma(m0 , shape=a0.shape, rate=scale)
 
      
 
      
scales  <- c(rep(DEscales, each=slides), rep(EEscales, each=2*slides)) # same as p
+
scales  <- c(rep(DEscales, each=nreps), rep(EEscales, each=2*nreps))       
      
 
 
X <- rgamma(n* p, a.shape, rate=scales)  
 
X <- rgamma(n* p, a.shape, rate=scales)  
dim(X) <- c(p, n)
+
dim(X) <- c(n,p)
 +
 
 
X <- t(X)
 
X <- t(X)
 +
 +
# Graphical check
 +
hist(kDE, prob=TRUE)
 +
lines(density(kDE))
 +
 +
hist(kEE, prob=TRUE)
 +
lines(density(kEE))
 +
 +
Xbar <- rowMeans(log2(X))
 +
hist(Xbar, breaks=30, prob=TRUE)
 +
lines(density(Xbar))
 +
pairs(log2(X))

Latest revision as of 00:38, 6 June 2007

Code snipits and programs written in R, S or S-PLUS

  1. p (genes) by n (slides) matrix
  2. m=p keeping fdr notation

m <- p <- 1000 nreps <- 5

n <- nreps * 2 pi0 <- 0.95

m1 <- round(m * (1-pi0)) m0 <- p - m1

params <- c(2.74886, 1.36546, 4.12844) # "IPTG-a parameters"

a.shape <- params[1] a0.shape <- params[2] scale <- params[3]

DEscales <- rgamma(2*m1, shape=a0.shape, rate=scale) EEscales <- rgamma(m0 , shape=a0.shape, rate=scale)

scales <- c(rep(DEscales, each=nreps), rep(EEscales, each=2*nreps)) X <- rgamma(n* p, a.shape, rate=scales) dim(X) <- c(n,p)

X <- t(X)

  1. Graphical check

hist(kDE, prob=TRUE) lines(density(kDE))

hist(kEE, prob=TRUE) lines(density(kEE))

Xbar <- rowMeans(log2(X)) hist(Xbar, breaks=30, prob=TRUE) lines(density(Xbar)) pairs(log2(X))