Difference between revisions of "ExamineConvest.R"

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(Much more efficient way of obtaining iterations)
(tol tests)
 
(One intermediate revision by the same user not shown)
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#{{R}}
 
#{{R}}
 
library(limma)
 
library(limma)
 
+
 
# Load local copy of convest
 
# Load local copy of convest
 
source("convest.R")
 
source("convest.R")
 
+
 
# ------------- Generating a mixture of normally distributed data ------------- #
 
# ------------- Generating a mixture of normally distributed data ------------- #
 
simNorm <- function(m=1000, pi0=0.8, mu0=0, mu1=3, sigma=1) {
 
simNorm <- function(m=1000, pi0=0.8, mu0=0, mu1=3, sigma=1) {
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   return(pvalues)
 
   return(pvalues)
 
}
 
}
 
+
 
simNorm2 <- function(m=1000, pi0=0.8, mu0=0, s1=1, s2=3) {
 
simNorm2 <- function(m=1000, pi0=0.8, mu0=0, s1=1, s2=3) {
 
   m1 <- round(m * (1-pi0))  
 
   m1 <- round(m * (1-pi0))  
 
   m0 <- m - m1
 
   m0 <- m - m1
 
   means <- rep(0,m)
 
   means <- rep(0,m)
  #c(rep(mu1,m1), rep(mu0,m0))
 
 
   sigma <- c(rep(s2,m1), rep(s1,m0))
 
   sigma <- c(rep(s2,m1), rep(s1,m0))
 
   DEflag <- as.logical(sigma - min(sigma))
 
   DEflag <- as.logical(sigma - min(sigma))
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   return(pvalues)
 
   return(pvalues)
 
}
 
}
 
 
#  ---------------------------------------------------------------------------- #
 
#  ---------------------------------------------------------------------------- #
# Multtest does not allow a max of 1 (NA) going into smooth.spline
 
  
 
#convest arguement doreport=TRUE provides iteration information
 
#convest arguement doreport=TRUE provides iteration information
pvalues <- simNorm2(m=50)
+
pvalues <- simNorm(m=500, pi0=0.25)
 +
 
 +
 
 +
# 1) Illustrating that modified convest function is identical to limma version
 +
limma::convest(pvalues, niter=50, doreport=TRUE)
 +
convest(pvalues, niter=50, doreport=TRUE)
 +
 
  
convest(pvalues, niter=500, doreport=TRUE, file="conv.txt")
+
# 2) Writing report information to file
 +
convest(pvalues, niter=100, doreport=TRUE, file="conv.txt")
 
conv <- read.table("conv.txt", header=TRUE, as.is=TRUE)
 
conv <- read.table("conv.txt", header=TRUE, as.is=TRUE)
  
 
# Interestingly the convergence rate varies if m is small
 
# Interestingly the convergence rate varies if m is small
 
 
plot(conv$pi0, type="l")
 
plot(conv$pi0, type="l")
 
plot(diff(conv$pi0), type="l")
 
plot(diff(conv$pi0), type="l")
  
# weighted average of convest iterations after removing burnin period
+
# Weighted average of convest iterations after removing burnin period
 
# Raw
 
# Raw
 
mean(conv$pi0[-(1:10)])
 
mean(conv$pi0[-(1:10)])
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weighted.mean(conv$pi0[-(1:10)], w=seq(0,1, length=length(conv$pi0[-(1:10)])))
 
weighted.mean(conv$pi0[-(1:10)], w=seq(0,1, length=length(conv$pi0[-(1:10)])))
  
convest(pvalues, niter=50)
+
# 3) Tolerance adjustment
 +
convest(pvalues, niter=300, doreport=TRUE, file="conv.txt", tol=1e-6)
 +
conv <- read.table("conv.txt", header=TRUE, as.is=TRUE)
 +
 
 +
X11()
 +
plot(conv$pi0, type="l")
 +
plot(diff(conv$pi0), type="l")

Latest revision as of 23:55, 24 June 2007

Code snipits and programs written in R, S or S-PLUS library(limma)

  1. Load local copy of convest

source("convest.R")

  1. ------------- Generating a mixture of normally distributed data ------------- #

simNorm <- function(m=1000, pi0=0.8, mu0=0, mu1=3, sigma=1) {

 m1 <- round(m * (1-pi0)) 
 m0 <- m - m1
 means <- c(rep(mu1,m1), rep(mu0,m0))
 DEflag <- as.logical(means)
 X <- rnorm(m, means, sigma)
 pvalues <- 2*(1-pnorm(abs(X),0,sigma))
 return(pvalues)

}

simNorm2 <- function(m=1000, pi0=0.8, mu0=0, s1=1, s2=3) {

 m1 <- round(m * (1-pi0)) 
 m0 <- m - m1
 means <- rep(0,m)
 sigma <- c(rep(s2,m1), rep(s1,m0))
 DEflag <- as.logical(sigma - min(sigma))
 X <- rnorm(m, means, sigma)
 pvalues <- 2*(1-pnorm(abs(X),0,s1))
 return(pvalues)

}

  1. ---------------------------------------------------------------------------- #
  1. convest arguement doreport=TRUE provides iteration information

pvalues <- simNorm(m=500, pi0=0.25)


  1. 1) Illustrating that modified convest function is identical to limma version

limma::convest(pvalues, niter=50, doreport=TRUE) convest(pvalues, niter=50, doreport=TRUE)


  1. 2) Writing report information to file

convest(pvalues, niter=100, doreport=TRUE, file="conv.txt") conv <- read.table("conv.txt", header=TRUE, as.is=TRUE)

  1. Interestingly the convergence rate varies if m is small

plot(conv$pi0, type="l") plot(diff(conv$pi0), type="l")

  1. Weighted average of convest iterations after removing burnin period
  2. Raw

mean(conv$pi0[-(1:10)])

  1. Weighted mean

weighted.mean(conv$pi0[-(1:10)], w=seq(0,1, length=length(conv$pi0[-(1:10)])))

  1. 3) Tolerance adjustment

convest(pvalues, niter=300, doreport=TRUE, file="conv.txt", tol=1e-6) conv <- read.table("conv.txt", header=TRUE, as.is=TRUE)

X11() plot(conv$pi0, type="l") plot(diff(conv$pi0), type="l")